All I will suggest is read the label. It's all going to depend on what you are trying to kill and how mature it is.
As a general rule I mix mine at 2%, but for perennial weeds or mature weeds you often need a "hotter" mix. Spot treatment tend to be listed as percentages, while spraying larger areas tend to suggest a maximum amount of chemical applied per acre. This means you can use as much or as little water as a carrier for the chemical as long as you disperse it evenly over that acre area.