I have a yearly attack by Japanese Beetles on my apple trees, I've been using Permethrin, which is the man-made version of the naturally occurring Pyrethrum, and one application does the job, but Permethrin isn't labeled for edible crops and my apples are starting to produce pretty good, so this year I'm switching to Malathion, which is a popular insecticide for fruit trees, hopefully it's as effective as the Permethrin was. The reason why I picked Malathion over Sevin is because Malathion is more effective on aphids and I've observed some on my trees. Other than dormant oil I don't spray my fruit trees unless it's a life and death situation like the Japanese beetles, but if i have to spray anyway I want to target as many problem insects as I can.